Collagen fibrillogenesis in situ: fibril segments become long fibrils as the developing tendon matures.

@article{Birk1997CollagenFI,
  title={Collagen fibrillogenesis in situ: fibril segments become long fibrils as the developing tendon matures.},
  author={David E. Birk and Emanuel I Zycband and Sarah J. Woodruff and Donald A. Winkelmann and R. L. Trelstad},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1997},
  volume={208 3},
  pages={
          291-8
        }
}
Tissue architecture, stability, and mechanical attributes are all determined by the structure and organization of collagen fibrils. Therefore, the characterization of fibril growth steps and determination of how this growth is regulated is essential to the elucidation of how tissues are assembled. We have proposed that fibril segments are intermediates in the formation of mature fibrils. The purpose of this study was to determine the length and structure of fibrils within a relatively mature… CONTINUE READING
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