Collagen fibrillogenesis in situ: fibril segments undergo post-depositional modifications resulting in linear and lateral growth during matrix development.

@article{Birk1995CollagenFI,
  title={Collagen fibrillogenesis in situ: fibril segments undergo post-depositional modifications resulting in linear and lateral growth during matrix development.},
  author={David E. Birk and Maria V. Nurminskaya and Emanuel I. Zycband},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1995},
  volume={202 3},
  pages={229-43}
}
Elucidating how collagen fibril growth is regulated is important in determining how tissues are assembled. Fibrils are deposited as segments. The growth of these segments is an important determinant of tissue architecture, stability, and mechanical attributes. Fibril segments were isolated from developing tendons and their structure characterized. The post-depositional changes leading to linear and lateral growth of fibrils also were examined. Segments extracted from 14-day chicken embryo… CONTINUE READING
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