Collagen fibril organisation in mammalian vitreous by freeze etch/rotary shadowing electron microscopy.

@article{Bos2001CollagenFO,
  title={Collagen fibril organisation in mammalian vitreous by freeze etch/rotary shadowing electron microscopy.},
  author={Kees Jan Bos and David F. Holmes and Roger S. Meadows and Karl E Kadler and David McLeod and Paul N. Bishop},
  journal={Micron},
  year={2001},
  volume={32 3},
  pages={301-6}
}
Mammalian vitreous gel contains two major network-forming polymeric systems: long, thin fibrils comprising predominantly type II collagen and a meshwork of hyaluronan. The gel structure is maintained primarily by the collagen component, but little is known about the mechanisms of spacing of the collagen fibrils and of interactions between fibrils to form a stable network. In this study we have applied the technique of freeze etching/rotary shadowing electron microscopy in order to reveal the… CONTINUE READING