Collagen fibre implant for tendon and ligament biological augmentation. In vivo study in an ovine model

@article{Enea2012CollagenFI,
  title={Collagen fibre implant for tendon and ligament biological augmentation. In vivo study in an ovine model},
  author={Davide Enea and Jessica H. Gwynne and Simon Kew and Meera Arumugam and Jennifer Shepherd and Roger A. Brooks and Siddhartha Ghose and Serena M. Best and Ruth Elizabeth Cameron and Neil Rushton},
  journal={Knee Surgery, Sports Traumatology, Arthroscopy},
  year={2012},
  volume={21},
  pages={1783-1793}
}
Although most in vitro studies indicate that collagen is a suitable biomaterial for tendon and ligament tissue engineering, in vivo studies of implanted collagen for regeneration of these tissues are still lacking. The objectives of this study were the following: (1) to investigate the regeneration of the central third of the ovine patellar tendon using implants made of an open array of collagen fibres (reconstituted, extruded bovine collagen); and (2) to compare two collagen crosslinking… CONTINUE READING
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