Collagen fiber alignment and biaxial mechanical behavior of porcine urinary bladder derived extracellular matrix.

@article{Gilbert2008CollagenFA,
  title={Collagen fiber alignment and biaxial mechanical behavior of porcine urinary bladder derived extracellular matrix.},
  author={Thomas W. Gilbert and Silvia Wognum and Erinn M Joyce and Donald O Freytes and Michael S. Sacks and Stephen F. Badylak},
  journal={Biomaterials},
  year={2008},
  volume={29 36},
  pages={4775-82}
}
The collagen fiber alignment and biomechanical behavior of naturally occurring extracellular matrix (ECM) scaffolds are important considerations for the design of medical devices from these materials. Both should be considered in order to produce a device to meet tissue specific mechanical requirements (e.g., tendon vs. urinary bladder), and could ultimately affect the remodeling response in vivo. The present study evaluated the collagen fiber alignment and biaxial mechanical behavior of ECM… CONTINUE READING