Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice.

@article{Smith2014CollagenCD,
  title={Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice.},
  author={Lucas R. Smith and Elisabeth R. Barton},
  journal={American journal of physiology. Cell physiology},
  year={2014},
  volume={306 10},
  pages={C889-98}
}
Many skeletal muscle diseases are associated with progressive fibrosis leading to impaired muscle function. Collagen within the extracellular matrix is the primary structural protein providing a mechanical scaffold for cells within tissues. During fibrosis collagen not only increases in amount but also undergoes posttranslational changes that alter its organization that is thought to contribute to tissue stiffness. Little, however, is known about collagen organization in fibrotic muscle and its… CONTINUE READING
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