Collagen-based matrices with axially oriented pores.

  title={Collagen-based matrices with axially oriented pores.},
  author={Marta Madaghiele and Alessandro Sannino and Ioannis Vassilios Yannas and Myron Spector},
  journal={Journal of biomedical materials research. Part A},
  volume={85 3},
The aim of this work was the implementation of a simple technique for the production of cylindrical collagen-based scaffolds with axially oriented pore channels. Matrices with this particular porous structure have the potential to improve the regeneration of peripheral nerves and spinal cord by physically supporting and guiding the growth of neural structures across the site of injury. The regenerative potential may be further enhanced when the collagen scaffold is used as a delivery vehicle… CONTINUE READING