Collagen XIV is important for growth and structural integrity of the myocardium.

  title={Collagen XIV is important for growth and structural integrity of the myocardium.},
  author={Ge Tao and Agata K Levay and Jacqueline D. Peacock and Danielle J. Huk and Sarah N Both and Nicole H. Purcell and Jose R Pinto and Maarten L. Galantowicz and Manuel Koch and Pamela A. Lucchesi and David E. Birk and Joy Lincoln},
  journal={Journal of molecular and cellular cardiology},
  volume={53 5},
Collagen XIV is a fibril-associated collagen with an interrupted triple helix (FACIT). Previous studies have shown that this collagen type regulates early stages of fibrillogenesis in connective tissues of high mechanical demand. Mice null for Collagen XIV are viable, however formation of the interstitial collagen network is defective in tendons and skin leading to reduced biomechanical function. The assembly of a tightly regulated collagen network is also required in the heart, not only for… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 44 references

The extracellular matrix: at the center of it all.

Journal of molecular and cellular cardiology • 2010
View 8 Excerpts
Highly Influenced

Extracellular matrix and heart development.

Birth defects research. Part A, Clinical and molecular teratology • 2011
View 3 Excerpts

Transverse aortic constriction in mice.

Journal of visualized experiments : JoVE • 2010
View 1 Excerpt

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