Collaborative ocular melanoma study randomized trial of I-125 brachytherapy.

  title={Collaborative ocular melanoma study randomized trial of I-125 brachytherapy.},
  author={Barbara S. Hawkins},
  journal={Clinical trials},
  volume={8 5},
BACKGROUND Although findings from observational studies published in the 1970s and early 1980s suggested that length of remaining life after a diagnosis of uveal melanoma was similar following enucleation (removal of the eye) and local eye-conserving radiotherapy, the majority of ophthalmologists in the United States were not convinced that "saving the eye" would not compromise survival. PURPOSE The Collaborative Ocular Melanoma Study (COMS) was designed to compare enucleation and… CONTINUE READING