Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras

@article{Boehmer1975CollaborationOH,
  title={Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras},
  author={Harald von Boehmer and Lynn Hudson and Jonathan Sprent},
  journal={The Journal of Experimental Medicine},
  year={1975},
  volume={142},
  pages={989 - 997}
}
T-B collaboration has been studied in a secondary response to sheep erythrocytes using either syngeneic or allogeneic T- and B-cell combinations. T cells prepared from tetraparental bone marrow chimeras (TBMC), carrying H-2 determinants of one parental strain only, cooperated with syngeneic, as well as with allogeneic B cells carrying the alloantigens to which the T cells had been tolerized in the chimeric environment. When TBMC-derived cells of a single H-2 specificity were transferred with a… CONTINUE READING

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A rapid method for the isolation of functional thymus-derived murine lymphocytes

J digestible immunoadsorbent
Eur . J . Immunol • 1973

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