Collaboration of helper and cytotoxic T lymphocytes.

@article{Stuhler1993CollaborationOH,
  title={Collaboration of helper and cytotoxic T lymphocytes.},
  author={Gernot Stuhler and Peter Walden},
  journal={European journal of immunology},
  year={1993},
  volume={23 9},
  pages={
          2279-86
        }
}
Cytotoxic T lymphocytes are major effector cells in response to viral infections and in allograft rejection and are implicated in many other immunological reactions. Efficient induction of cytotoxic activity in these cells in many but not all cases depends upon helper T and antigen-presenting cells so that at least three different cell types have to work together. Here we present an in vitro model for the helper T cell-dependent induction of cytotoxic T lymphocytes which allows the… CONTINUE READING
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