Collaborating with the Enemy: Function of Macrophages in the Development of Neoplastic Disease

@inproceedings{Eljaszewicz2013CollaboratingWT,
  title={Collaborating with the Enemy: Function of Macrophages in the Development of Neoplastic Disease},
  author={Andrzej Eljaszewicz and Małgorzata Wiese and Anna Helmin-Basa and Michal Jankowski and Lidia Gackowska and Izabela Kubiszewska and Wojciech Kaszewski and Jacek Michalkiewicz and Wojciech Zegarski},
  booktitle={Mediators of inflammation},
  year={2013}
}
Due to the profile of released mediators (such as cytokines, chemokines, growth factors, etc.), neoplastic cells modulate the activity of immune system, directly affecting its components both locally and peripherally. This is reflected by the limited antineoplastic activity of the immune system (immunosuppressive effect), induction of tolerance to neoplastic antigens, and the promotion of processes associated with the proliferation of neoplastic tissue. Most of these responses are macrophages… CONTINUE READING
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