Collaborating with the Enemy: Function of Macrophages in the Development of Neoplastic Disease

  title={Collaborating with the Enemy: Function of Macrophages in the Development of Neoplastic Disease},
  author={Andrzej Eljaszewicz and Małgorzata Wiese and Anna Helmin-Basa and Michal Jankowski and Lidia Gackowska and Izabela Kubiszewska and Wojciech Kaszewski and Jacek Michalkiewicz and Wojciech Zegarski},
  booktitle={Mediators of inflammation},
Due to the profile of released mediators (such as cytokines, chemokines, growth factors, etc.), neoplastic cells modulate the activity of immune system, directly affecting its components both locally and peripherally. This is reflected by the limited antineoplastic activity of the immune system (immunosuppressive effect), induction of tolerance to neoplastic antigens, and the promotion of processes associated with the proliferation of neoplastic tissue. Most of these responses are macrophages… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 18 extracted citations


Publications referenced by this paper.
Showing 1-10 of 109 references

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer

  • M.A.Venneri, M.DePalma, M. Ponzoni
  • Blood, vol. 109, no. 12, pp. 5276– 5285, 2007.
  • 2007
Highly Influential
10 Excerpts

Tumour-associatedmacrophages (TAMS): disordered function, immune suppression and progressive tumour growth

  • B. Al-Sarireh andO. Eremin
  • Journal of the Royal College of Surgeons of…
  • 2000
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…