Colitis-associated cancer: the role of T cells in tumor development


Chronic inflammation severely increases the risk for cancer development as seen in patients with inflammatory bowel disease (IBD). Although the exact mechanisms of inflammation-associated tumor development remain to be shown, a role for the adaptive immune system has been implicated in colitis-associated cancer (CAC). In fact, CD4+ effector T cells, which… (More)
DOI: 10.1007/s00281-009-0161-8


2 Figures and Tables

Cite this paper

@article{Waldner2009ColitisassociatedCT, title={Colitis-associated cancer: the role of T cells in tumor development}, author={Maximilian J. Waldner and Markus F Neurath}, journal={Seminars in Immunopathology}, year={2009}, volume={31}, pages={249-256} }