Colicin E1 plasmid as a probe for detection and study of anti-dna activity in SLE sera.

@article{Casperson1980ColicinEP,
  title={Colicin E1 plasmid as a probe for detection and study of anti-dna activity in SLE sera.},
  author={Gerald F. Casperson and Edward W. Voss},
  journal={Journal of immunological methods},
  year={1980},
  volume={36 3-4},
  pages={293-308}
}
Tritiated colicin E1 plasmid DNA ([3H]DNA) was purified, characterized and developed as a test antigen for study of anti-DNA antibody activity in a modified Farr assay. The homogeneous molecular weight (4.2 X 10(6) daltons), physical state (intact covalently closed circles), and capacity for intrinsic radioactive labeling to a suitable specific activity… CONTINUE READING