Cold water stimulation of oropharyngeal receptors in man inhibits release of vasopressin.

@article{Salata1987ColdWS,
  title={Cold water stimulation of oropharyngeal receptors in man inhibits release of vasopressin.},
  author={Robert A Salata and Joseph G. Verbalis and Alan G. Robinson},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1987},
  volume={65 3},
  pages={561-7}
}
The act of drinking ameliorates thirst and inhibits the secretion of vasopressin before changes in extracellular fluid volume or osmolality in both animals and man. We evaluated whether this reflex inhibition of vasopressin secretion might be due to the presence of oropharyngeal receptors in humans. After dehydration, normal subjects (n = 4) were allowed to suck on ice chips for 30 min. Despite the absence of changes in plasma sodium (Na+) or osmolality, the mean plasma vasopressin level… CONTINUE READING

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The role of oropharnygeal receptors in thirst perception after dehydration and rehydration.

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