Cold-induced injury to porcine corneal endothelial cells and its mediation by chelatable iron: implications for corneal preservation.

Abstract

PURPOSE During hypothermic storage of the cornea, corneal endothelial damage restricts storage times. We previously reported a new, iron-dependent mechanism of cold-induced injury to cultured liver cells. In this study, we sought to evaluate whether corneal endothelial cells incur a similar kind of injury. METHODS Cultured porcine corneal endothelial… (More)

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