Cold exposure elevates cellular levels of messenger ribonucleic acid encoding thyrotropin-releasing hormone in paraventricular nucleus despite elevated levels of thyroid hormones.

@article{Zoeller1990ColdEE,
  title={Cold exposure elevates cellular levels of messenger ribonucleic acid encoding thyrotropin-releasing hormone in paraventricular nucleus despite elevated levels of thyroid hormones.},
  author={R. Thomas Zoeller and Nisreen H Kabeer and H Elliott Albers},
  journal={Endocrinology},
  year={1990},
  volume={127 6},
  pages={2955-62}
}
Cold exposure increases blood levels of TSH and thyroid hormones by stimulating the secretion of TRH from the median eminence. Thyroid hormones reduce TRH release and cellular levels of TRH mRNA. Using quantitative in situ hybridization to measure changes in cellular levels of various neuropeptide mRNAs, the present studies demonstrate that cold exposure… CONTINUE READING