Cold blood potassium diltiazem cardioplegia.

  title={Cold blood potassium diltiazem cardioplegia.},
  author={John Standeven and Michael Jellinek and L J Menz and Ronald J Kolata and Hendrick Boyer Barner},
  journal={The Journal of thoracic and cardiovascular surgery},
  volume={87 2},
Despite the use of cold blood potassium (CBK) cardioplegia, the severely impaired myocardium and/or long ischemia time continue to be a challenge. Because of the association of Ca++ with cell injury and death, the use of Ca++ entry blockers is logical. Investigation of cold blood diltiazem (CBD) revealed no advantages over CBK cardioplegia. The combination of potassium and diltiazem is appropriate because of their different mechanisms of action. Ten dogs had 1 hour of myocardial ischemia with… CONTINUE READING