Colchicine myotoxicity: case reports and literature review.

@article{Wilbur2004ColchicineMC,
  title={Colchicine myotoxicity: case reports and literature review.},
  author={Kerry Wilbur and Mark J Makowsky},
  journal={Pharmacotherapy},
  year={2004},
  volume={24 12},
  pages={
          1784-92
        }
}
Two of our patients experienced myotoxicity associated with colchicine administration. The first was a 54-year-old woman who was receiving dialysis and came to the emergency department with progressive generalized weakness and vomiting. She recently had taken colchicine for the treatment of gout. Physical examination revealed proximal muscle weakness and tenderness on palpation. Her creatine kinase (CK), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) levels were elevated… CONTINUE READING
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