Colchicine inhibited the expression of tissue inhibitor of metalloprotenase-1 and interleukin-6 in cultured activated hepatic stellate cells

Abstract

Cultured HSCs were treated colchicine with different concentrations for 12 h, respectively. The effects of colchicine on HSCs growth were measured by MTT assay. Effects of colchicine on gene expression of HSCs were analysed by using a self-made oligonucleotide microarray. Colchicine inhibited HSCs growth in a dose-dependent manner. After 12 h of treatment… (More)
DOI: 10.1007/BF02836697

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