Colchicine in addition to conventional therapy for acute pericarditis: results of the COlchicine for acute PEricarditis (COPE) trial.

@article{Imazio2005ColchicineIA,
  title={Colchicine in addition to conventional therapy for acute pericarditis: results of the COlchicine for acute PEricarditis (COPE) trial.},
  author={Massimo Imazio and Marco Bobbio and Enrico Cecchi and Daniela Demarie and Brunella Demichelis and Franco Pomari and Mauro Moratti and Gianni Gaschino and Massimo Giammaria and Aldo Ghisio and Riccardo Belli and Rita Trinchero},
  journal={Circulation},
  year={2005},
  volume={112 13},
  pages={2012-6}
}
BACKGROUND Colchicine is effective and safe for the treatment and prevention of recurrent pericarditis and might ultimately serve as the initial mode of treatment, especially in idiopathic cases. The aim of this work was to verify the safety and efficacy of colchicine as an adjunct to conventional therapy for the treatment of the first episode of acute pericarditis. METHODS AND RESULTS A prospective, randomized, open-label design was used. A total of 120 patients (mean age 56.9+/-18.8 years… CONTINUE READING
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