• DOI:10.1136/heartjnl-2020-317108
Corpus ID: 220305546

Colchicine for acute and chronic coronary syndromes

@article{Imazio2020ColchicineFA,
  title={Colchicine for acute and chronic coronary syndromes},
  author={M. Imazio and Alessandro Andreis and A. Brucato and Y. Adler and G. D. de Ferrari},
  journal={Heart},
  year={2020},
  volume={106},
  pages={1555 - 1560}
}

M. Imazio, Alessandro Andreis, +2 authors G. D. de Ferrari

Published 2020

Medicine

Heart

Colchicine is an ancient drug, traditionally used for the treatment and prevention of gouty attacks; it has become standard of treatment for pericarditis with a potential role in the treatment of coronary artery disease. Atherosclerotic plaque formation, progression, destabilisation and rupture are influenced by active proinflammatory cytokines interleukin (IL)-1β and IL-18 that are generated in the active forms by inflammasomes, which are cytosolic multiprotein oligomers of the innate immune… CONTINUE READING

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