Cola‐induced hypokalaemia: a super‐sized problem

  title={Cola‐induced hypokalaemia: a super‐sized problem},
  author={Craig Packer},
  journal={International Journal of Clinical Practice},
  • C. Packer
  • Published 1 June 2009
  • Business
  • International Journal of Clinical Practice
way into medical journals [8]. Indeed, an emerging topic is the meta-analysis of meta-analyses (a metameta-analysis) [9]. Part of the explosion of interest has been the automation of statistical testing. The ‘heavy lifting’ is no longer the calculation of effect sizes and confidence intervals, but the searching for, acquisition of, and inputting of data from relevant clinical trials. The Cochrane Collaboration, a global network of researchers maintains an informative website (http://www… 
It’s Published!
Initial citation rates for case reports are lower than that for other article types, such as meta-analyses and randomized trials, but case report citations tend to accrue steadily over time; long-term citation rates might be more appropriate for comparison.
Effects of cola intake on fertility: a review
The cola effects on reproduction including pregnancy miscarriages, ovulatory and menstrual disorders, and reduced semen quality are introduced, suggesting justification of limitations in the maximum recommended daily dose of these soft drinks.
Erosive Potential of Bottled Salad Dressings.
The study shows that some bottled dressings have erosive potential even higher than orange Juice and patients should be informed accordingly, whereas dressings containing calcium-rich products (enriched with milk and/or cream) (French-type) caused lower enamel wear than orange juice.
Soft Drinks Associate with Low Levels of Some Bone and Infertility Markers in Women
Assessment of the effect of soft drink consumption on the serum levels of some bone and infertility markers in women found that consumption of soft drinks might be associated with high inorganic phosphates and reduced serum level of serum progesterone.
Assessment and management of dental erosion.
Functional foods/ingredients on dental erosion
The objective of this overview is to summarize the effective strategies for dietary modification to prevent dental erosion.
Analysis of the erosive effect of different dietary substances and medications
Erosive challenge caused a statistically significant reduction in SH for all agents except for coffee, some medications and alcoholic drinks, and non-flavoured mineral waters, teas and yogurts (P < 0·01).
Protective benefits of a stabilised stannous-containing fluoride dentifrice against erosive acid damage.
The potential for the stabilised, Sn-containing NaF dentif Rice to provide erosion protection benefits that are not significantly different from the positive control benchmark for erosion protection (stabilised SnF2), and are significantly better than a broad range of dentifrice formulations available on the European market are supported.
Randomized in situ clinical trial evaluating erosion protection efficacy of a 0.454% stannous fluoride dentifrice
The stannous fluoride dentif rice demonstrated significantly greater erosion protection efficacy relative to the NaF/triclosan dentifrice in this randomized in situ clinical trial.
Dental Erosion – An Overview with Emphasis on Chemical and Histopathological Aspects
Dental erosion starts by initial softening of the enamel surface followed by loss of volume with a softened layer persisting at the surface of the remaining tissue, thus altering its strength and structure.


Chronic hypokalemia due to excessive cola consumption: a case report
Doctors should ask patients about soft drink consumption when they encounter unexplained hypokalemia, because fructose absorption in the small bowel is relatively inefficient, this probably led to an osmotic diarrhea and GI potassium wasting.
Upper gastrointestinal cancer and economic deprivation – data from a London (UK) Cancer Network
  • P. Stott
  • Medicine
    International journal of clinical practice
  • 2009
Cola drinks need to be added to the physician’s checklist of drugs and substances (such as liquorice) that can cause hypokalaemia, and the soft drink industry needs to promote safe and moderate use of its products for all age groups, reduce serving sizes and pay heed to the rising call for healthier drinks.
Serum potassium, cardiovascular risk, and effects of an ACE inhibitor: results of the HOPE study.
In patients at high cardiovascular risk, modest hypokalemia predicts a less favorable outcome while modest hyperkalemia does not, and ramipril reduces hypokAlemia and decreases risk.
Serum potassium and risk of cardiovascular disease: the Framingham heart study.
In a community-based sample of individuals free of cardiovascular disease and not taking medications that affect potassium homeostasis, serum potassium level was not associated with risk of cardiovascular Disease.
Carbonated Beverages and Chronic Kidney Disease
Drinking 2 or more colas per day was associated with increased risk of chronic kidney disease, and preliminary results suggest that cola consumption may increase the risk of Chronic kidney disease.
Caffeine and hypokalemia.
This data indicates that a significant decrease in the serum potassium concentration at therapeutic levels of theophylline (1,3-dimethylxa) is associated with lowered serum potassium levels in patients with high plasma potassium levels.
Coca-Cola and kangaroos
Caffeine and hypokale
  • Ann Intern Med
  • 1986
Liquid Candy: How Soft Drinks are Harming America’s Health [Internet], 2nd edn. Washington, DC: Center for Science in the Public Interest; c2005
  • Liquid Candy Supplement. Soft Drink Consumption:1999–2002
  • 2002
Aroq Ltd; c2009. Global: soft drinks consumption rises in 2007 -research