Coiled bodies and U2 snRNA genes adjacent to coiled bodies are enriched in factors required for snRNA transcription.

@article{Schul1998CoiledBA,
  title={Coiled bodies and U2 snRNA genes adjacent to coiled bodies are enriched in factors required for snRNA transcription.},
  author={Wouter Schul and Roel van Driel and Luitzen de Jong},
  journal={Molecular biology of the cell},
  year={1998},
  volume={9 5},
  pages={1025-36}
}
A significant percentage of the gene clusters that contain the human genes for U1 small nuclear RNA (snRNA) or for U2 snRNA have been found associated with small nuclear domains, known as coiled bodies. We show here, by immunofluorescent labeling of human cells, that coiled bodies are enriched in factors required for the transcription of these snRNA genes. The 45-kDa gamma-subunit of the transcription factor, proximal element sequence-binding transcription factor (PTF), which is specific for… CONTINUE READING

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A significant percentage of the gene clusters that contain the human genes for U1 small nuclear RNA ( snRNA ) or for U2 snRNA have been found associated with small nuclear domains , known as coiled bodies .
A significant percentage of the gene clusters that contain the human genes for U1 small nuclear RNA ( snRNA ) or for U2 snRNA have been found associated with small nuclear domains , known as coiled bodies .
A significant percentage of the gene clusters that contain the human genes for U1 small nuclear RNA ( snRNA ) or for U2 snRNA have been found associated with small nuclear domains , known as coiled bodies .
A significant percentage of the gene clusters that contain the human genes for U1 small nuclear RNA ( snRNA ) or for U2 snRNA have been found associated with small nuclear domains , known as coiled bodies .
The 45-kDa gamma - subunit of the transcription factor , proximal element sequence - binding transcription factor ( PTF ) , which is specific for the snRNA genes , was found in high concentrations in coiled bodies , along with the general transcription factor TATA - box binding protein and a subset of RNA polymerase II .
The 45-kDa gamma - subunit of the transcription factor , proximal element sequence - binding transcription factor ( PTF ) , which is specific for the snRNA genes , was found in high concentrations in coiled bodies , along with the general transcription factor TATA - box binding protein and a subset of RNA polymerase II .
The 45-kDa gamma - subunit of the transcription factor , proximal element sequence - binding transcription factor ( PTF ) , which is specific for the snRNA genes , was found in high concentrations in coiled bodies , along with the general transcription factor TATA - box binding protein and a subset of RNA polymerase II .
The 45-kDa gamma - subunit of the transcription factor , proximal element sequence - binding transcription factor ( PTF ) , which is specific for the snRNA genes , was found in high concentrations in coiled bodies , along with the general transcription factor TATA - box binding protein and a subset of RNA polymerase II .
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