Cohort Removal Induces Changes in Body Temperature, Pain Sensitivity, and Anxiety-Like Behavior

@inproceedings{Takao2016CohortRI,
  title={Cohort Removal Induces Changes in Body Temperature, Pain Sensitivity, and Anxiety-Like Behavior},
  author={Keizo Takao and Hirotaka Shoji and Satoko Hattori and Tsuyoshi Miyakawa},
  booktitle={Front. Behav. Neurosci.},
  year={2016}
}
Mouse behavior is analyzed to elucidate the effects of various experimental manipulations, including gene mutation and drug administration. When the effect of a factor of interest is assessed, other factors, such as age, sex, temperature, apparatus, and housing, are controlled in experiments by matching, counterbalancing, and/or randomizing. One such factor that has not attracted much attention is the effect of sequential removal of animals from a common cage (cohort removal). Here we evaluated… CONTINUE READING
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