Cohesin – ein Proteinring für Genomstabilität und Chromatinfaltung

  title={Cohesin – ein Proteinring f{\"u}r Genomstabilit{\"a}t und Chromatinfaltung},
  author={Kerstin S. Wendt},
  • Kerstin S. Wendt
  • Published in BIOspektrum 2017
  • Biology
  • The cohesin complex has evolved as major player for structuring the chromatin fiber with roles in chromosome segregation, chromatin architecture, DNA damage repair and gene regulation. This article summarizes the latest discoveries and models for cohesin function and also reviews implications of the cohesin complex in developmental syndromes and cancer. 

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