Coherent manipulation of free amino acids fluorescence.

  title={Coherent manipulation of free amino acids fluorescence.},
  author={Ariana Rondi and Luigi Bonacina and Alexandre Trisorio and C M Hauri and J P Wolf},
  journal={Physical chemistry chemical physics : PCCP},
  volume={14 26},
Coherent manipulation of molecular wavepackets in biomolecules might contribute to the quest towards label-free cellular imaging and protein identification. We report the use of optimally tailored UV laser pulses in pump-probe depletion experiments that selectively enhance or decrease fluorescence between two aromatic amino acids: tryptophan (Trp) and tyrosine (Tyr). Selective fluorescence modulation is achieved with a contrast of ~35%. A neat modification of the time-dependent fluorescence… CONTINUE READING