Cografting with polymer-encapsulated human nerve growth factor-secreting cells and chromaffin cell survival and behavioral recovery in hemiparkinsonian rats.

Abstract

Encapsulated cell grafting is one approach for the delivery of neurotransmitters and/or neurotrophic factors to the brain. Baby hamster kidney (BHK) cells were genetically modified to secrete high levels of human nerve growth factor (hNGF). Following polymer encapsulation, these cells were implanted into the left lateral ventricle or the left striatum 1.5… (More)

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@article{Date1996CograftingWP, title={Cografting with polymer-encapsulated human nerve growth factor-secreting cells and chromaffin cell survival and behavioral recovery in hemiparkinsonian rats.}, author={Isao Date and Takashi Ohmoto and Tomonori Imaoka and Takahiko Ono and Joseph P. Hammang and Joel M. Francis and Cecilia Greco and Dwaine F. Emerich}, journal={Journal of neurosurgery}, year={1996}, volume={84 6}, pages={1006-12} }