Cognitive trio: relationship with major depression and clinical predictors in Han Chinese women


BACKGROUND Previous studies support Beck's cognitive model of vulnerability to depression. However, the relationship between his cognitive triad and other clinical features and risk factors among those with major depression (MD) has rarely been systematically studied. METHOD The three key cognitive symptoms of worthlessness, hopelessness and helplessness were assessed during their lifetime worst episode in 1970 Han Chinese women with recurrent MD. Diagnostic and other risk factor information was assessed at personal interview. Odds ratios (ORs) were calculated by logistic regression. RESULTS Compared to patients who did not endorse the cognitive trio, those who did had a greater number of DSM-IV A criteria, more individual depressive symptoms, an earlier age at onset, a greater number of episodes, and were more likely to meet diagnostic criteria for melancholia, postnatal depression, dysthymia and anxiety disorders. Hopelessness was highly related to all the suicidal symptomatology, with ORs ranging from 5.92 to 6.51. Neuroticism, stressful life events (SLEs) and a protective parental rearing style were associated with these cognitive symptoms. CONCLUSIONS During the worst episode of MD in Han Chinese women, the endorsement of the cognitive trio was associated with a worse course of depression and an increased risk of suicide. Individuals with high levels of neuroticism, many SLEs and high parental protectiveness were at increased risk for these cognitive depressive symptoms. As in Western populations, symptoms of the cognitive trio appear to play a central role in the psychopathology of MD in Chinese women.

DOI: 10.1017/S0033291713000160

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@inproceedings{Wang2013CognitiveTR, title={Cognitive trio: relationship with major depression and clinical predictors in Han Chinese women}, author={L. Wang and L. Liu and S. -H. Shi and J. Gao and Yi Liu and Y. Li and Z. Zhang and G. Wang and K. Zhang and M. Tao and C. Gao and K. Li and Xuemei Wang and L. Lv and G. H. Jiang and H. Y. Jia and Juan Zhang and C. Lu and C. Hu and Yumei Ning and J. Sun and T. Liu and Y. Zhang and Baowei Ha and H. Tian and H. Meng and J. Hu and Y. Chen and H. X. Deng and G. M. Huang and W. Wu and G. Li and X. Fang and J. Pan and X. Hong and Song Gao and X. Li and D. Yang and G. Chen and M. Cai and J. Dong and Q. B. Mei and Zhongxiang Shen and Raymond J Pan and Zhiqiang Liu and Yifang Tan and Jonathan Flint and Kenneth S. Kendler}, booktitle={Psychological medicine}, year={2013} }