Cognitive status of children treated with central nervous system prophylactic chemotherapy for acute lymphocytic leukemia.

@article{Brown1992CognitiveSO,
  title={Cognitive status of children treated with central nervous system prophylactic chemotherapy for acute lymphocytic leukemia.},
  author={Ronald Tse Brown and Avi Madan-Swain and Ray Pais and Robert G. Lambert and Kathleen Baldwin and Richard W. Casey and Nathan Frank and Sandra B Sexson and Abdal Ragab and Randy W. Kamphaus},
  journal={Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists},
  year={1992},
  volume={7 6},
  pages={481-97}
}
Treatment-related cognitive impairments have been reported for survivors of childhood leukemia following prophylactic central nervous system (CNS) treatment with craniospinal radiation. We examined the neurocognitive status of 46 children with acute lymphocytic leukemia (ALL) to assess the impact of a regimen consisting of systemic chemotherapy and prophylactic CNS chemotherapy. By comparing three groups of ALL children (i.e., patients whose diagnosis was recent, patients 1 year postdiagnosis… CONTINUE READING

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