Cognitive sequelae of head injury: involvement of basal forebrain and associated structures.

@article{Salmond2005CognitiveSO,
  title={Cognitive sequelae of head injury: involvement of basal forebrain and associated structures.},
  author={Claire Helen Salmond and Doris A. Chatfield and David K. Menon and John D. Pickard and Barbara J. Sahakian},
  journal={Brain : a journal of neurology},
  year={2005},
  volume={128 Pt 1},
  pages={189-200}
}
Traumatic brain injury is the most common cause of death and disability in young people and survivors often suffer from chronic cognitive deficits. From animal, post-mortem and cognitive studies, there is now increased evidence that abnormalities in the cholinergic system may be underlying some of these deficits. This study investigated this hypothesis in a group of survivors of moderate-severe head injury (n = 31). Patients completed a comprehensive neuropsychological assessment and an MRI… CONTINUE READING
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