Cognitive rehabilitation combined with drug treatment in Alzheimer's disease patients: a pilot study
@article{Bottino2005CognitiveRC, title={Cognitive rehabilitation combined with drug treatment in Alzheimer's disease patients: a pilot study}, author={C{\'a}ssio Machado Campos Bottino and Isabel A. M. Carvalho and Ana Maria M A Alvarez and Renata Thomas {\'A}vila and Patr{\'i}cia Ribeiro Zukauskas and Sonia E Zevallos Bustamante and Fl{\'a}via C Andrade and S{\'e}rgio Ricardo Hototian and Fabiana Saffi and C{\^a}ndida Helena P. Camargo}, journal={Clinical Rehabilitation}, year={2005}, volume={19}, pages={861 - 869} }
Objective: To study the efficacy of cognitive rehabilitation combined with acetylcholinesterase inhibitor (AChE-I) treatment in patients with mild Alzheimer's disease and their relatives. Method: Thirteen patients with mild Alzheimer's disease treated with rivastigmine 6-12 mg/day for more than two months started cognitive rehabilitation training. Before and after the cognitive rehabilitation training patients were assessed through cognitive tests, activities of daily living scale…
134 Citations
Effects of a multidisciplinar cognitive rehabilitation program for patients with mild Alzheimer's disease
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The intervention was associated with reduced depression symptoms for patients and caregivers and decreased neuropsychiatric symptoms in Alzheimer's subjects and the notion that structured nonpharmacological interventions can yield adjunct and clinically relevant benefits in dementia treatment is supported.
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A sample of 42 subjects with mild AD underwent clinical and cognitive evaluation and participated in a 6-month study with 2 experimental groups, finding that client-centered, global, cognitive therapy stimulated many cognitive functions and thus led to a better performance in language processing and ADL/IADL.
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Group NR is recommended for reducing psychiatric symptoms, and individualized NR for improving ADL, and NR at home either has no associated benefits, or the training sessions were not appropriately conducted by the caregiver.
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This study demonstrates the feasibility of a group-based Cognitive Rehabilitation program for patients with mild AD dementia and finds no significant effect on ADL, possibly reflecting a lack of transfer between the therapy setting and real life.
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Cognitive stimulation therapy has significant efficacy in lowering apathy and depression symptomatology and in the Mini Mental State Examination in patients with mild to moderate Alzheimer’s disease.
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The response to a CS treatment of some subjects over others is linked to cognitive and functional capacity, and this research contributes to characterize the neuropsychological profile that differentiates subjects who respond better than others before and after the treatment.
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- 2011
It is suggested that participation in a 6-month cognitive intervention can improve cognitive and non-cognitive functions in aMCI subjects and in contrast, AD patients showed no significant benefit from intervention.
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Cognitive intervention therapy as treatment for behaviour disorders in Alzheimer disease: evidence on efficacy and neurobiological correlations.
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Cognitive Rehabilitation Therapies for Alzheimer’s Disease: A Review of Methods to Improve Treatment Engagement and Self-Efficacy
- Psychology, MedicineNeuropsychology Review
- 2013
The goal is to stimulate discussion among researchers and clinicians alike on how treatment effects may be mediated by engagement in treatment, and what can be done to enhance patient adherence for cognitive rehabilitation therapies in order to obtain greater cognitive and functional benefits from the treatment itself.
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