Cognitive profile in spastic paraplegia with thin corpus callosum and mutations in SPG11.

@article{Siri2010CognitivePI,
  title={Cognitive profile in spastic paraplegia with thin corpus callosum and mutations in SPG11.},
  author={Laura Siri and Francesca Maria Battaglia and Alessandra Tessa and Andrea Rossi and Maja di Rocco and Sabrina Facchinetti and Monica Mascaretti and Filippo Maria Santorelli and E Veneselli and Roberta Biancheri},
  journal={Neuropediatrics},
  year={2010},
  volume={41 1},
  pages={35-8}
}
Autosomal recessive hereditary spastic paraplegia with thinning of the anterior corpus callosum (ARHSP-TCC) due to mutations in SPG11 on chromosome 15q (MIM610844) is the single most common cause of ARHSP. It is characterized by slowly progressive paraparesis and peripheral neuropathy. Although cognitive impairment, sometimes diagnosed as mental retardation… CONTINUE READING