Cognitive functioning in obsessive-compulsive disorder: a meta-analysis

  title={Cognitive functioning in obsessive-compulsive disorder: a meta-analysis},
  author={Na Young Shin and T. Y. Lee and E. Kim and Jun Soo Kwon},
  journal={Psychological Medicine},
  pages={1121 - 1130}
Background Substantial empirical evidence has indicated impairment in the cognitive functioning of patients with obsessive-compulsive disorder (OCD) despite inconsistencies. Although several confounding factors have been investigated to explain the conflicting results, the findings remain mixed. This study aimed to investigate cognitive dysfunction in patients with OCD using a meta-analytic approach. Method The PubMed database was searched between 1980 and October 2012, and reference lists of… 

Research Review: Neuropsychological test performance in pediatric obsessive-compulsive disorder--a meta-analysis.

A meta-analysis of the available literature on pediatric obsessive-compulsive disorder indicates that youth with OCD do not exhibit noteworthy neuropsychological deficits, in line with recent suggestions that OCD may not be characterized by clinically meaningful neuro psychological impairments.

Meta-Analysis Obsessive-Compulsive Disorder Is Associated With Broad Impairments in Executive Function : A

Obsessive-compulsive disorder (OCD) is a serious and often chronically disabling condition. The current dominant model of OCD focuses on abnormalities in prefrontal-striatal circuits that support

Neurocognitive function in paediatric obsessive-compulsive disorder

  • D. GellerA. Abramovitch S. Stewart
  • Psychology
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
  • 2018
While the OCD group performed in the normative range, these findings reveal relative weaknesses that may be overlooked, and may be of particular importance in clinical and school settings.

Executive Functioning in Chinese Patients With Obsessive Compulsive Disorder

The results do not seem to support the view that impaired executive functioning represents a basic cognitive and pathophysiological feature of Chinese patients with OCD, and additional research is required before this conclusion can be well accepted.

Neuropsychological Research in Obsessive-Compulsive Disorder: Current Status and Future Directions

Neuropsychological functions in obsessive-compulsive disorder (OCD) have been extensively investigated. Despite some common findings across studies indicating deficient test performance across

Executive impairments in Obsessive Compulsive Disorder: A systematic review with emotional and non-emotional paradigms.

There is some initial evidence for the existence of executive impairments in OCD, as expressed in the performance and/or processing of working memory inhibitory control and cognitive flexibility and initial evidence that these latter two could be modulated by the presentation or mental representation of negative valence stimuli or images, as well as the presence of aversive contingencies.



Neuropsychological function in obsessive-compulsive disorder.

Differences in Neuropsychological Performance Between Subtypes of Obsessive–Compulsive Disorder

Overall the results suggested greater impairments in performance on neuropsychological tasks in checkers relative to other subtypes of OCD, although the observed effects were small and the conclusions limited by the small subtype samples.

Neurocognitive dysfunction in patients with obsessive compulsive disorder.

The results suggest that OCD patients perform significantly worse on cognitive measures than controls, consistent with their poorer functional outcome, and indicate that on the basis of severity OCD patients are qualitatively distinguishable in neuropsychological terms, given their difference in the profiles of cognitive impairment.

Attention and cognition in patients with obsessive–compulsive disorder

The results show that patients with OCD have cognitive deficits, and the authors hypothesize that these deficits may be interpreted by attentional deficits caused by a dysfunctional anterior cingulate cortex.

Duration effect of obsessive–compulsive disorder on cognitive function: a functional MRI study

The results suggested that abnormal brain activation occurs in the early phase of OCD and that the long‐term persistence of OCD might involve a decline in cognitive function.

Cognitive Frontal Lobe Dysfunction in Obsessive-Compulsive Disorder

Neuropsychological deficits in obsessive-compulsive disorder: a comparison with unipolar depression, panic disorder, and normal controls.

Neuropsychological deficits were observed in patients with OCD that were not observed in matched patients with panic disorder or unipolar depression, and appears to be related to the specific illness processes associated with the disorder.

Neuropsychological performance of OCD patients before and after treatment with fluoxetine: evidence for persistent cognitive deficits

The data suggest that cognitive impairments in OCD are not secondary to symptoms and therefore form a trait feature of the disorder, in line with recent evidence that serotonin mediates cognitive functions of orbitofrontal cortex to a greater extent than those associated with dorsolateral prefrontal regions.