Cognitive functioning in children with sickle cell disease: a meta-analysis.

  title={Cognitive functioning in children with sickle cell disease: a meta-analysis.},
  author={Jeffrey Schatz and Robert L Finke and Julie M Kellett and Joel H. Kramer},
  journal={Journal of pediatric psychology},
  volume={27 8},
OBJECTIVE To establish whether sickle cell disease (SCD) affects cognitive functioning in children with no evidence of cerebral infarction. METHODS We conducted a meta-analysis of studies of cognition in SCD to determine the size of any statistical difference between children with SCD and controls. Methodological factors were evaluated according to the size and frequency of group differences. RESULTS There were small but reliable decrements in cognitive functioning on IQ measures (4.3-point… CONTINUE READING


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