Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed.

@article{Sheline2006CognitiveFI,
  title={Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed.},
  author={Yvette I. Sheline and Deanna M. Barch and Keith S. Garcia and Kenneth Gersing and Carl Pieper and Kathleen Welsh-Bohmer and David C. Steffens and P. Murali Doraiswamy},
  journal={Biological psychiatry},
  year={2006},
  volume={60 1},
  pages={58-65}
}
BACKGROUND A number of studies have examined clinical factors linked to worse neuropsychological performance in late life depression (LLD). To understand the influence of LLD on cognition, it is important to determine if deficits in a number of cognitive domains are relatively independent, or mediated by depression- related deficits in a basic domain such as processing speed. METHODS Patients who met DSM-IV criteria for major depression (n = 155) were administered a comprehensive… CONTINUE READING
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