Cognitive enhancement in man with ispronicline, a nicotinic partial agonist

Abstract

Cholinergic mechanisms are clearly involved in memory deficits associated with Alzheimer's disease (AD) (Perry et al., 1977). Recently, there has been growing interest in the nicotinic approach to the treatment of AD; however, compounds have failed in the clinic because of a lack of separation between central and peripheral nicotinic effects (Potter et al… (More)
DOI: 10.1385/JMN:30:1:169

Topics

2 Figures and Tables

Slides referencing similar topics