Cognitive enhancement in man with ispronicline, a nicotinic partial agonist


Cholinergic mechanisms are clearly involved in memory deficits associated with Alzheimer's disease (AD) (Perry et al., 1977). Recently, there has been growing interest in the nicotinic approach to the treatment of AD; however, compounds have failed in the clinic because of a lack of separation between central and peripheral nicotinic effects (Potter et al… (More)
DOI: 10.1385/JMN:30:1:169


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