Cognitive endophenotypes in OCD: a study of unaffected siblings of probands with familial OCD.

@article{Viswanath2009CognitiveEI,
  title={Cognitive endophenotypes in OCD: a study of unaffected siblings of probands with familial OCD.},
  author={Biju Viswanath and Y. C. Janardhan Reddy and Keshav Janakiprasad Kumar and T. K. Kandavel and Channapatna R. Chandrashekar},
  journal={Progress in neuro-psychopharmacology & biological psychiatry},
  year={2009},
  volume={33 4},
  pages={610-5}
}
BACKGROUND Impairments in executive functions and non-verbal memory are considered potential endophenotype markers of obsessive-compulsive disorder (OCD). For the neuropsychological deficits to be considered endophenotypes, they should be demonstrable in unaffected family members. AIM To compare the neuropsychological performance in unaffected siblings of probands with familial OCD with that of individually matched healthy controls. METHODS Twenty-five unaffected siblings of OCD probands… CONTINUE READING
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