Cognitive efficiency declines over time in adults with Type 1 diabetes: effects of micro- and macrovascular complications

@article{Ryan2003CognitiveED,
  title={Cognitive efficiency declines over time in adults with Type 1 diabetes: effects of micro- and macrovascular complications},
  author={Dr. C. M. Ryan and M. O. Geckle and Trevor John Orchard},
  journal={Diabetologia},
  year={2003},
  volume={46},
  pages={940-948}
}
Mild cognitive dysfunction is not uncommon in adults with Type 1 diabetes, but its pathogenesis remains unclear. Previous cross-sectional studies had suggested that microangiopathy might affect brain integrity and lead to 'central neuropathy.' To assess the relationship between changes in cognitive performance and the incidence of new micro- and macrovascular complications, 103 young and middle-aged adults (mean age: 40 yrs) with childhood-onset Type 1 diabetes were followed over a 7-year… CONTINUE READING