Cognitive effects of hormonal therapy in older adults.

Abstract

There is ample preclinical evidence that gonadal steroids (estrogens and androgens) play an important role in central nervous system development and function. The abrupt decline of estrogen levels in women after menopause, and the slower, subtler decline in total and bioavailable testosterone serum levels that occurs in aging men ("andropause," "male… (More)
DOI: 10.1053/j.seminoncol.2008.08.002

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