Cognitive dysfunction in schizophrenia: comparison of treatment with atypical antipsychotic agents and conventional neuroleptic drugs.

@article{Gallhofer1996CognitiveDI,
  title={Cognitive dysfunction in schizophrenia: comparison of treatment with atypical antipsychotic agents and conventional neuroleptic drugs.},
  author={Bernd Gallhofer and Ute Bauer and Stefanie Lis and Stephan Krieger and Harald Gruppe},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={1996},
  volume={6 Suppl 2},
  pages={S13-20}
}
Impaired cognitive function is both a feature of schizophrenia and a side effect of conventional neuroleptics. Maze tests were used to determine the effects on cognition of conventional dopamine antagonist neuroleptics (haloperidol and fluphenazine) and the newer serotonin-dopamine antagonist antipsychotics (risperidone and clozapine). Patients on clozapine or risperidone showed better performance on the maze tasks than untreated patients or patients taking conventional neuroleptics. In… CONTINUE READING

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