Cognitive dysfunction and white matter abnormalities in systemic lupus erythematosus.

  title={Cognitive dysfunction and white matter abnormalities in systemic lupus erythematosus.},
  author={Elizabeth Kozora and Christopher M. Filley},
  journal={Journal of the International Neuropsychological Society : JINS},
  volume={17 3},
Brain abnormalities have been documented by neuropsychological assessment as well as a variety of neuroimaging techniques in patients with systemic lupus erythematosus (SLE). Conventional neuroimaging in patients with neuropsychiatric disease (NPSLE) typically discloses periventricular white matter (WM) hyperintensities, infarcts, hemorrhages, and cerebral atrophy. In SLE patients with none of these findings, sophisticated neuroimaging techniques have recently supported associations between… CONTINUE READING
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