Cognitive deficits in progressive supranuclear palsy, Parkinson's disease, and multiple system atrophy in tests sensitive to frontal lobe dysfunction.

@article{Robbins1994CognitiveDI,
  title={Cognitive deficits in progressive supranuclear palsy, Parkinson's disease, and multiple system atrophy in tests sensitive to frontal lobe dysfunction.},
  author={T. W. Robbins and M G James and Adrian M. Owen and Klaus W. Lange and A. J. Lees and Peter Nigel Leigh and C. David Marsden and Niall Quinn and Brian Alan Summers},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={1994},
  volume={57 1},
  pages={79-88}
}
Groups of patients with idiopathic Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy or Steele-Richardson-Olszewski syndrome, matched for overall clinical disability, were compared using three computerised cognitive tests previously shown to be sensitive to frontal lobe dysfunction. On a test of planning based on the Tower of London task, all three groups were impaired, but in different ways. The groups with palsy and Parkinson's disease were slower in the measure… CONTINUE READING