Cognitive deficits and decreased locomotor activity induced by single-walled carbon nanotubes and neuroprotective effects of ascorbic acid

@inproceedings{Liu2014CognitiveDA,
  title={Cognitive deficits and decreased locomotor activity induced by single-walled carbon nanotubes and neuroprotective effects of ascorbic acid},
  author={Xudong Liu and Yuchao Zhang and Jinquan Li and Yuzhe Liu and Yang Wu and Yan Lin Li and Zhisong Lu and Samuel C T Yu and Rui Li and Xu Yang},
  booktitle={International journal of nanomedicine},
  year={2014}
}
Single-walled carbon nanotubes (SWCNTs) have shown increasing promise in the field of biomedicine, especially in applications related to the nervous system. However, there are limited studies available on the neurotoxicity of SWCNTs used in vivo. In this study, neurobehavioral changes caused by SWCNTs in mice and oxidative stress were investigated. The results of ethological analysis (Morris water maze and open-field test), brain histopathological examination, and assessments of oxidative… CONTINUE READING
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