Cognitive decline strongly correlates with cortical atrophy in Alzheimer’s dementia

@article{Mouton1998CognitiveDS,
  title={Cognitive decline strongly correlates with cortical atrophy in Alzheimer’s dementia},
  author={Peter R. Mouton and Lee J. Martin and Michael E. Calhoun and Gloria Dal Forno and Donald L. Price},
  journal={Neurobiology of Aging},
  year={1998},
  volume={19},
  pages={371-377}
}
Alzheimer's disease (AD) is characterized by progressive dementia and distinct neuropathology at autopsy. In order to test the relationship between dementia severity and loss of brain volumes, we prospectively documented the neurological/medical health of 26 male and 26 female controls and AD cases, and evaluated a subset of controls and AD cases using the Mini Mental State Examination (MMSE). At autopsy, Consortium to Establish a Registry for Alzheimer's Disease (CERAD) criteria confirmed… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 49 CITATIONS

The Aging Brain Part I

VIEW 9 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 38 REFERENCES

Neocortical neuron number in humans: effect of sex and age.

  • The Journal of comparative neurology
  • 1997
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL