Cognitive decline correlates with neuropathological stage in Parkinson's disease.

@article{Braak2006CognitiveDC,
  title={Cognitive decline correlates with neuropathological stage in Parkinson's disease.},
  author={Heiko Braak and Udo R{\"u}b and Kelly del Tredici},
  journal={Journal of the neurological sciences},
  year={2006},
  volume={248 1-2},
  pages={255-8}
}
Recently, the relationship between cognitive status and the neuropathological stages of a newly proposed staging procedure for Parkinson's disease (PD) was assessed in a cohort of 88 individuals. None of the patients had received the clinical diagnosis of dementia with Lewy bodies. The topographic distribution pattern of the cerebral Lewy body pathology was evaluated semiquantitatively in alpha-synuclein immunoreactions. MMSE scores from the last neurological examination prior to death were… CONTINUE READING