Cognitive changes in patients with Huntington’s disease (HD) and asymptomatic carriers of the HD mutation

@article{MSc2004CognitiveCI,
  title={Cognitive changes in patients with Huntington’s disease (HD) and asymptomatic carriers of the HD mutation},
  author={J. Lemiere MSc and Marleen Decruyenaere and Gerry Evers-Kiebooms and Erik Vandenbussche and Prof. Dr. R. Dom},
  journal={Journal of Neurology},
  year={2004},
  volume={251},
  pages={935-942}
}
Objective information about the onset and progression of cognitive impairment in Huntington’s disease (HD) is very important in the light of appropriate outcome measures when conducting clinical trials. Therefore, we evaluated the progression of cognitive functions in HD patients and asymptomatic carriers of the HD mutation (AC) over a 2.5–year period.We also sought to detect the earliest markers of cognitive impairment in AC. A prospective study comparing HD patients, clinically asymptomatic… CONTINUE READING

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