Cognitive behavioural therapy as an adjunct to pharmacotherapy for primary care based patients with treatment resistant depression: results of the CoBalT randomised controlled trial.

@article{Wiles2013CognitiveBT,
  title={Cognitive behavioural therapy as an adjunct to pharmacotherapy for primary care based patients with treatment resistant depression: results of the CoBalT randomised controlled trial.},
  author={Nicola Wiles and Laura J Thomas and Anna Abel and Nicola Ridgway and Nicholas Turner and John Campbell and Anne Garland and Sandra Hollinghurst and Bill Jerrom and David Kessler and Willem Kuyken and Jill Morrison and Katrina M. Turner and Chris R Williams and Tim J. Peters and Glyn Lewis},
  journal={Lancet},
  year={2013},
  volume={381 9864},
  pages={375-84}
}
BACKGROUND Only a third of patients with depression respond fully to antidepressant medication but little evidence exists regarding the best next-step treatment for those whose symptoms are treatment resistant. The CoBalT trial aimed to examine the effectiveness of cognitive behavioural therapy (CBT) as an adjunct to usual care (including pharmacotherapy) for primary care patients with treatment resistant depression compared with usual care alone. METHODS This two parallel-group multicentre… CONTINUE READING