Cognitive and psychiatric abnormalities in multiple sclerosis.

  title={Cognitive and psychiatric abnormalities in multiple sclerosis.},
  author={Ronald C. Petersen and Emre Kokmen},
  journal={Mayo Clinic proceedings},
  volume={64 6},
In multiple sclerosis, behavioral changes, including alterations in cognitive functions and psychiatric abnormalities, have been recognized with increasing frequency in recent years. Multiple sclerosis formerly was thought to be primarily a disorder of the brain stem and spinal cord; however, functional changes that can be attributed, at least in part, to cerebral dysfunction are being recognized. Certain cognitive functions such as memory and conceptual processes seem to be preferentially… CONTINUE READING