Cognitive and neurologic outcomes after coronary-artery bypass surgery.

@article{Selnes2012CognitiveAN,
  title={Cognitive and neurologic outcomes after coronary-artery bypass surgery.},
  author={O. Selnes and R. Gottesman and M. Grega and W. Baumgartner and S. Zeger and G. Mckhann},
  journal={The New England journal of medicine},
  year={2012},
  volume={366 3},
  pages={
          250-7
        }
}
For patients undergoing coronary-artery bypass grafting (CABG), adverse neurologic outcomes, including stroke and cognitive decline, are major concerns. Even mild cognitive deficits before surgery may be a marker for cerebrovascular disease and increased risk. 

Paper Mentions

Observational Clinical Trial
During the last decades improvements in operative techniques and perioperative care have led to a steady decline in mortality after cardiac surgery. Good survival rates have been shown… Expand
ConditionsCognitive Dysfunction, Coronary Artery Bypass
InterventionProcedure
Depression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (Neuropsychiatric Outcomes After Heart Surgery study)
Prior research on cognitive and functional outcomes after coronary artery bypass graft (CABG) surgery has largely explored these two domains in isolation. In this study, we assess baseline depressionExpand
Coronary revascularization and stroke.
The SYNTAX (SYNergy Between PCI With TAXUS and Cardiac Surgery) trial ([1][1]) was designed to determine whether treatment of complex coronary artery disease with percutaneous coronary interventionExpand
Cerebral dysfunction after coronary artery bypass surgery
TLDR
Preoperative cerebrovascular evaluation and adaptation of surgical strategies will provide preventative approaches for cerebral dysfunction after CABG and identifying changes in brains of aged individuals undergoing cardiac surgery may improve strategies for preventing cerebral dysfunction. Expand
Understanding noncardiac complications following coronary artery bypass graft surgery
TLDR
In this Review, the noncardiac complications of CABG are discussed including etiology, pathophysiology, treatment and prevention. Expand
Cognitive Outcomes After Heart Valve Surgery: A Systematic Review and Meta‐Analysis
TLDR
Evidence on cognitive outcomes after heart valve surgery is summarized, and whether aortic and mitral valve surgery are associated with different cognitive outcomes is examined. Expand
Postoperative cognitive dysfunction after cardiac surgery
TLDR
A systematic review on the research into postoperative cognitive dysfunction in noncardiac surgery to ascertain the status of the evidence and to examine the methodologies used in studies found many studies were found to be underpowered and a number of other methodologic difficulties were identified. Expand
Coronary-Artery Bypass Grafting.
TLDR
When performing coronary artery bypass grafting (CABG), several decisions need to be made: the coronary vessel to be grafted, the choice of conduit, and the approach on cardiopulmonary bypass, off pump. Expand
Coronary-Artery Bypass Grafting.
TLDR
Coronary artery bypass grafting (CABG pronounced 'cabbage') may be performed as a primary procedure, after failed PCI, or as a repeat procedure. Expand
Neurologic Complications of Cardiac Surgery
TLDR
Intraoperative and perioperative guidelines for heart surgery have recently been published or updated with the aim of minimizing the risk of brain ischemia. Expand
Coronary artery revascularizations and cognitive decline - A systematic review.
TLDR
There is a need for more studies on long-term cognitive outcomes after coronary artery revascularizations, as the findings indicate an evidence gap in the current understanding of long- term outcomes following coronary arteries revascularization. Expand
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References

SHOWING 1-10 OF 70 REFERENCES
Predictors of cognitive decline following coronary artery bypass graft surgery.
TLDR
Patients with noncoronary manifestations of atherosclerosis, chronic disabling neurologic illness, or limited social support are at risk for cognitive decline after CABG surgery, and more years of education were associated with less cognitive decline. Expand
Cognitive Outcomes in Elderly High-Risk Patients After Off-Pump Versus Conventional Coronary Artery Bypass Grafting: A Randomized Trial
TLDR
In elderly high-risk patients, no significant difference was found in the incidence of cognitive dysfunction 3 months after either OPCAB or CCAB, and no difference in incidence of Cognitive dysfunction between the groups regardless of the definition applied. Expand
Do management strategies for coronary artery disease influence 6-year cognitive outcomes?
TLDR
Compared with subjects with no vascular disease risk factors, the CAD patients had lower baseline cognitive performance and greater degrees of decline over 72 months, suggesting that in these patients, vascular disease may have an impact on cognitive performance. Expand
Cognitive outcomes after on- versus off-pump coronary artery bypass surgery.
TLDR
At baseline, lower cognitive function, older age, lower education, and ethnicity other than white were predictive of cognitive decline after CABG, as well as compare cognitive outcomes between treatment arms. Expand
Risk factors for early or delayed stroke after cardiac surgery.
TLDR
Most strokes after cardiac surgery occurred after initial uneventful recovery from surgery, and women were at higher risk to suffer early and delayed perioperative strokes. Expand
Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients.
TLDR
It is believed beating heart CABG is associated with a lower incidence of stroke and may therefore improve patient outcomes, and multivariable analysis revealed 10 variables that were independent predictors of stroke. Expand
Neurocognitive outcomes of off-pump versus on-pump coronary artery bypass: a prospective randomized controlled trial.
TLDR
Off-pump coronary artery bypass graft surgery did not result in decreased frequency of neurocognitive deficit and was associated with substantially lower levels of troponin release after surgery. Expand
The impact of aortic manipulation on neurologic outcomes after coronary artery bypass surgery: a risk-adjusted study.
TLDR
The incidence of postoperative stroke increases with increased levels of aortic manipulation, and this work has shown that off-pump CABG reduces stroke rates by minimizing aortsic manipulation. Expand
Pulse Pressure and Risk of Adverse Outcome in Coronary Bypass Surgery
TLDR
An increase in pulse pressure was independently and significantly associated with greater fatal and nonfatal adverse cerebral and cardiac outcomes in patients having CABG surgery, highlighting the associated risks of preoperative PP on acute postoperative vascular outcomes. Expand
Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery.
TLDR
The course of cognitive change during the five years after CABG and the effect of perioperative decline on long-term cognitive function were determined. Expand
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